Metabolic Health
MOTS-c, GLP-1 medicines and what is being studied for metabolic aging.
GLP-1 microdosing for longevity: what the evidence actually shows
A careful, sourced look at low-dose (“microdosed”) GLP-1 for metabolic healthspan: what people mean by it and why they do it, what the SELECT trial and other human evidence do and do not support, what is known about side effects at low doses, and why the longevity case is still a hypothesis.
MOTS-c benefits: what the metabolic research actually shows
A sourced guide to MOTS-c, the mitochondrial-derived “exercise peptide”: what it is, the benefits people use it for, what the mouse and human studies measured, the “before and after” question, what is known about side effects, how it gets stacked, and what the longevity community is saying.
MOTS-c side effects: what is actually known about its safety in people
An honest look at MOTS-c side effects: why human safety data is thin, what the one completed trial of a MOTS-c analog reported, what the mouse studies did and did not measure, how long studies have dosed it, and what the longevity community is saying.